Coats’ disease

• A retinal vasculopathy
• M>F
• Idiopathic, non-hereditary
• Breakdown of the inner blood-retinal barrier in the endothelial cells
• Leakage of blood products, cholesterol crystals and lipid-laden macrophages into the retina and subretinal space
• Onset typically 6-8 years old
• 80% unilateral