Paediatric Glaucoma

Primary congenital glaucoma

• Rare syndrome of angle dysgenesis causing reduced aqueous outflow

• Bilateral in 70%

• M>F

• Usually sporadic (10% familial). GLC3 A-D genes implicated (eg. CYP1B1 is at GLC3A)

• Usually diagnosed within the first year

• Technically termed primary juvenile glaucoma