Leucocoria

Differential diagnosis of leucocoria

• Tumours: retinoblastoma, leukaemia, astrocytic hamartoma (retinal astrocytoma), combined retinal hamartoma
• Congenital: cataract, persistent fetal vasculature, coloboma, Norrie’s, incontinentia pigmenti
• Vascular: ROP, Coat’s, familial exudative vitreoretinopathy
• Trauma: vitreous haemorrhage, RD
• Inflammatory/infective: toxocariasis, toxoplasmosis, endophthalmitis, posterior uveitis