Foetal Alcohol Syndrome

Microphthalmos

Coloboma

Hypoplastic optic nerve

Narrow ferehead

Blepharophimosis

• Blepharophimosis-ptosis-epicanthus inversus syndrome. Features

  • Blepharophimosis (narrowed palpebral fissure)
  • Telecanthus (wide intercanthal distance)
  • Ptosis
  • Epicanthus inversus (extra skin fold from the lower lid extending to the upper lid and covering the medial canthus)

• Autosomal dominant: FOXL2 gene on chromosome 3

• Inherited 5:1 from males as most women with the condition have early loss of ovarian function

• High risk of amblyopia due to ptosis interfering with the visual axis

Strabismus

Telecanthus

Anterior segment dysgenesis (Peter’s and Axenfeld’s anomalies)