Behcet's disease

Idiopathic, chronic, multisystem disorder

Recurrent episodes of acute inflammation

Commonest ophthalmic manifestation: sight-threatening panuveitis and retinal vasculitis

Typically affects young adults

Middle eastern ethnicity

Family history

HLA-B51 allele (higher rate of ocular involvement)

• Common in Japan

Also the HLA-B12 allele…