Strabismus

Exotropia

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Commonest childhood strabismus in South East Asia

Causes a crossed diplopia: right image comes from left eye and vice versa

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In exotropic patients, always exclude:

  • Nerve palsies (eg. third nerve)

  • Muscle restriction: orbital fracture, thyroid eye disease, orbital inflammation, craniofacial abnormalities

  • Sensory exotropias: cataract, glaucoma, retinal disease etc.

  • Consecutive exotropia

Constant exotropias

  • Infantile/congenital

    • Large deviation present at both near and distance
    • Presents at 2-6 months
    • Normal refraction
    • Often associated CNS abnormalities (in contrast with congenital eso)
    • DVD
    • Requires surgical treatment
  • Basic exotropia

    • Exotropia equal for distance and near
    • Presents after 6 months
    • Surgical treatment

Intermittent exotropia

  • Presents later (typically between 2 and 5 years)

  • Intervening moments of normal alignment

  • Often starts as an exophoria that decompensates with fatigue, inattention, bright light, illness

  • Most common type of exo

  • There is:

    • Suppression when the eyes are deviated
    • Good stereoacuity when aligned
    • Large convergence amplitudes
    • Amblyopia is rare
  • Phases of intermittent exotropia (aim for surgery when they progress beyond 1)

    • 1. Exophoria at distance and orthophoria for near when the patient is tired or daydreaming
    • 2. Exotropic at distance and exophoric for near. Suppression prevents diplopia
    • 3. Exotropic for near and distance.

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Newcastle Control Score for grading intermittent exotropia (total out of 7)

  • Home control (subjective)

    • 0: never noticed

    • 1: exotropia or monocular eye closure for <50% of the time for distance

    • 2: exotropia or monocular eye closure for >50% of the time for distance

    • 3: exotropia or monocular eye closure for distance and near

  • Clinic control near (objective)

    • 0: only visible with cover test and immediately restores fixation

    • 1: blinks/refixates to restore fixation after cover test

    • 2: deviation is visible spontaneously (without cover)

  • Clinic control distance (objective)

    • As for near
  • If 3 or higher: consider surgery

Simulated distance exotropia (aka pseudo-divergence excess)

  • Appears worse for distance
  • High AC:A
  • Tenacious proximal convergence/fusion masks larger deviation for near: can be unmasked by 1 hour of monocular occlusion (patch test), prism adaptation testing or by using a +3.00D lens
    • If after the test the exo is equal for distance and near, then it is a pseudo-divergence excess

True distance exotropia (divergence excess)

  • Rare
  • AC:A may be normal or high (which carries risk of overcorrection after surgery)
  • Deviation >10PD for distance

Near exotropia (convergence insufficiency)

  • Exotropic for near, exophoric for distance
  • Associated with myopia or presbyopia
  • Affects young adults: aesthenopia, diplopia for reading

Convergence insufficiency: not a true exotropia

  • Exophoric for near
  • Causes aesthenopia, especially in teenagers

Treatment for intermittent exotropia

  • Refractive error correction: myopic correction can relax divergence and correct exo.
    • Overminusing hypermetropes can also be considered
  • Manage amblyopia
  • Orthoptic exercises (eg. pencil push-ups) and diplopia awareness
  • Occasionally prisms, botox
  • Surgery

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Indications for muscle surgery for exotropia

  • Increasing deviation

  • Increasing breakdown/progression through stages

  • Reducing stereopsis

  • Abnormal head posture

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