Pharmacology
Parasympathetic Neurotransmission
- Acetylcholine is the major neurotransmitter: formed from choline and acetyl coenzyme A (CoA)
- Inactivated by acetylcholinesterase to acetic acid and choline
- Two receptor types
- Muscarinic: at the effect organs (postganglionic)
- G-protein coupled receptor
- Nicotinic: ganglionic synapses and neuromuscular junction
- Ligand-gated…