Genetics
Mutations
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Get access- Any permanent change in DNA
- Can occur at multiple levels
- Genome: most common. Due to chromosome missegregation
- Chromosome: due to chromosome rearrangements
Gene: least common, mainly due to the activity of DNA repair enzymes (repair 99.9% of all replication errors)
- Can also be caused by extrinsic factors:
- UV or ionising radiation
- Chemicals