Pharmacology
Glucocorticoids
- Applied topically, subconjunctivally, systemically to suppress inflammation
- Mechanisms of action
- Reduce the number of PMLs, lymphocytes, macrophages
- Affect vascular permeability
- Inhibit phospholipase A2 and the eicosanoids
- Inhibit histamine release
- Inhibit cytokine gene transcription in lymphocytes and APCs
- Side effects
- Cataract:…