Physiology
Cutaneous Receptors
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Get access- Meissner’s corpuscles: light touch
Pacinian corpuscles and Ruffini’s endings (in skin): pressure, mechanical deformation and vibration
- Merkel discs: light touch
- Free nerve endings: pain, mechanical deformation and temperature
- Bradykinin, serotonin, histamine and acetylcholine can activate chemical pain receptors
Prostaglandins and substance P enhance sensitivity of pain receptors but don’t directly stimulate them